Study of exteraction of trace diazepam in water samples using Modified NanoTube carboxyl as sorbent

Document Type : Original Article

Authors

• ali moghimi ¹
• Milad Abniki ²
• Fatemeh Hajikarimi ²

¹ Associated professor analytical chemistry Department of Chemistry, Varamin( Pishva )Branch Islamic Azad University, Varamin, Iran

² 30 METRY NIROYHAVAI street 4th,No.7 , 7.33 alley

Abstract

The presented method is used for the separation and pre-concentration of diazepam drug in aqueous samples. In this research, new techniques of dispersive solid phase extraction of small amounts of pharmaceutical effluents as an indicator of diazepam drug in aqueous samples by modified carboxylated carbon nanotubes. And its measurement was used by visible and ultraviolet spectroscopy in real samples. These techniques are a two-phase system in which the phase giver is aqueous samples containing diazepam and the receiver phase is carbon nanotubes functionalized with carboxylate. The experiments were performed in two stages of extracting the desorbed aqueous samples of diazepam drug using ammonia solvent and the desorbed samples were submitted to the UV-Vis spectrophotometer for further analysis. This method is cheap, simple, and fast, and it is compatible with many existing methods. A sensitive and reliable method was used to extract, pre-concentrate, and measure small amounts of diazepam. The concentration of ions in the solution was measured by flame atomic absorption spectrometry. The concentration factor was 20, the detection limit of the method (LOD) was 1.2 µg. L-1 and the relative standard deviation was 3.19%.

Keywords

• Functionalized Multi Wall Carbon NanoTube carboxyl(MWCNT-COOH)
• UV-Vis spectrophotometery
• Diazepam drug

---